Antidepressants and weight gain. The hows and whys of this aren't quite clear.

They used the antidepressant citalopram (Celexa Jul 2, 2024 · Duloxetine was associated with an average gain of 1. adults 20 to 59 years of age. Others gain weight due to increased appetite and reduced physical activity. 2024 Jul 2. An electronic health records study of long-term weight gain following antidepressant use. 7 kilograms compared with a placebo Abstract. We usually th Oct 15, 2010 · Article Abstract Objective: Psychotropic drugs often induce weight gain, leading to discomfort and discontinuation of treatment and, more importantly, increasing the risk of obesity-related illnesses such as diabetes mellitus, hypertension, and coronary heart disease. Desvenlafaxine (Pristiq) and weight gain – this antidepressant is considered very low Mar 31, 2023 · Antidepressants That Can Cause Weight Gain. This narrative review discusses the propensity of various antipsychotics to cause weight Weight gain following antidepressant treatment may, therefore, be a sign of re-covery from depression and may be viewed positively by patients. Find out whether it’s a concern for people taking Celexa, a type of SSRI. Some people gain weight when taking a certain Aug 22, 2017 · Antipsychotic-induced weight gain is a major management problem for clinicians. Jul 2, 2024 · One antidepressant contributed to a small amount of weight loss at six months, the study found. May 26, 2023 · Adverse Effects. In the year of study entry, 13% of men and 22% of women were prescribed antidepressants. That's because weight gain while taking an antidepressant is complicated. If you enter your antidepressant, it will tell you what side effects are possible. [1] While each person responds to antidepressants differently, some antidepressant medications are more likely to cause weight gain than others. 4 days ago · Side effects of antidepressants vary from one medicine to another and from person to person. In this context, antidepressants have attracted lesser attention than anti-psychotic agents and mood stabilizers. The use of these drugs is increasing propensity of individual antidepressants to result in weight gain. Serotonin is one of the chemical messengers (neurotransmitters) that carry signals between brain nerve cells (neurons). The SSRIs like Prozac, Zoloft (the most commonly prescribed antidepressant), Lexapro, Celexa, and Paxil are . AKA, it’s easy to gain weight if you have a reason to pin it on. During 1 836 452 person years of follow-up, the incidence of new episodes of ≥5 weight gain in participants not prescribed antidepressants was 8. The severity of the weight gain varies with the drug, with some causing weight gain Oct 1, 2018 · But a study published May 23, 2018, in The BMJ suggests that antidepressants are also associated with sustained weight gain. Find out which SSRIs are more likely to cause weight gain, and how mindful eating, exercise, and switching medications can help. Oct 4, 2019 · Some antidepressants may increase your appetite, resulting in weight gain, while others may cause nausea. Discuss possible major side effects with your health care provider or pharmacist. Additionally, some antidepressants can cause fluid retention or bloating, which can contribute to temporary weight gain. Jun 19, 2018 · Wellbutrin did not cause weight gain, however this did not work for my depression. Weight gain is also associated with the atypical antidepressant Remeron (mirtazapine). Jul 24, 2019 · Why do you gain weight with antidepressants and mood stabilizers?In this video I discuss two way. Some antidepressants are more likely than others to cause sexual side effects. Some of the antidepressants most commonly associated with weight gain include: Weight gain is one of the most common side effects of these medications. There is evidence that antidepressant drugs may induce a variable amount of weight gain, but results are sparse and often Antidepressants and Weight Gain - MGH Center for Women's Mental Health. Indeed, anti-depressants greatly differ in their ability to induce weight gain, and a better knowledge of the effect of each drug on weight would be extremely helpful. Weight gain is one common side effect of certain classes of antidepressants including selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs), and monoamine oxidase inhibitors (MAOIs). If you or someone you know has suicidal thoughts when taking an antidepressant, immediately contact your doctor or get emergency help. This is an app I use to search for and track side effects. A 2022 study found that fluoxetine could cause weight loss of up to 2. Serotonin is a hormone that regulates mood and Antidepressants that can cause wait gain include: Atypical antipsychotic medications (such as Risperdal, Abilify and Zyprexa) Selective serotonin reuptake inhibitors (SSRIs) (such as Paxil, Remeron and Zoloft ) Both the likelihood of weight gain and the amount of possible weight gain vary from drug to drug. The most prevalent side effects of antidepressants include sexual dysfunction, drowsiness, weight gain, insomnia, anxiety, dizziness, headache, dry mouth, blurred vision, nausea, rash, and tremor. (2000). Studies of Wellbutrin SR show that 14% of people taking a dose of 300 mg per day lost Jan 20, 2022 · Zoloft (sertraline) Get coupon. No, it’s not inevitable. “Bupropion (Wellbutrin and Zyban) on average had a 15% lower risk of gaining a clinically Apr 18, 2021 · Weight gain has been a persistent side effect since the first antidepressant was identified in the late l950s. •. “In our study, the average weight at baseline was 84 kg In fact, significant weight loss or gain is one of the symptoms used to diagnose depression. 78 kilograms) at 24 months. This is an excellent, complex, and clinically important question. Bothersome side effects, such as dry mouth, nausea, weight gain or sexual side effects, can make it difficult to stick with treatment. May 2, 2023 · One is through changes in appetite and cravings, which can result in increased caloric intake. These include: Apr 17, 2024 · Antidepressants and Weight Gain . Selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors One of the most widely prescribed antidepressants, sertraline, also known by brand names Zoloft and Lustral, was associated with an average gain of nearly 0. You also may become less anxious and fidget/pace less, burning less calories as a result. Similarly, not all medications for sleep cause weight gain; one that has been associated with weight gain is diphenhydramine (the active ingredient in Benadryl that is also used in many over-the-counter sleep aids). Sep 29, 2023 · Sertraline: Weight Gain and Antidepressants. It Jul 5, 2024 · Buproprion was associated with the least amount of weight gain, while antidepressants like escitalopram and paroxetine were associated with the most weight gain. 0%) men and 35 307 (22. Wellbutrin, Pristiq, and Effexor are also Apr 18, 2021 · Weight gain has been a persistent side effect since the first antidepressant was identified in the late l950’s. 2 per 100 Dec 23, 2020 · Pamelor has been shown to cause weight gain while Tofranil is less likely to add weight. Mar 26, 2019 · Why weight gain happens. 1. Nov 17, 2018 · An antidepressant isn't always a direct cause of weight gain. The study found that the most used medications among the participant group were sertraline (Zoloft), citalopram (Celexa), and bupropion Apr 1, 1988 · Weight gain is an often reported, but incompletely understood, side effect of many antidepressant medications. Maintenance. Overall, Celexa seems to be one of the best-tolerated SSRIs for many people. Weight changes probably have more to do with changing appetite rather than changing metabolism. Best antidepressant for anxiety and depression. 4-year study was around 0. The Journal of Clinical Psychiatry, 61(Suppl11), 37–41. Weight gain is a relatively common problem during both acute and long-term treatment with antidepressants, and it is an important Antidepressants are the most commonly prescribed medications for U. The hows and whys of this aren't quite clear. researchers determined the long-term associations between antidepressant prescriptions and weight gain in about 300,000 patients who had three or more body-mass index measurements between 2004 and 2014. Aug 11, 2017 · The mean annual weight gain among antidepressant users during this 4. 5 pounds (0. Objective: Psychotropic drugs often induce weight gain, leading to discomfort and discontinuation of treatment and, more importantly, increasing the risk of obesity-related illnesses such as diabetes mellitus, hypertension, and coronary heart disease. It has been shown that weight gain and obesity lead to increased cardiovascular and cerebrovascular morbidity and mortality, reduced quality of life and poor drug compliance. Whether it worked for a close relative. Monoamine oxidase inhibitors (MAOIs) inhibit an enzyme involved in the metabolism of biogenic amines (eg, norepinephrine, epi-nephrine, dopamine, serotonin) and xenobiot-ic amines (eg, tyramine, ephedrine, phenyl-ephrine). (2001). Best antidepressant for energy and motivation. Patients may also describe asthenia and malaise while on antidepressant therapy. “Bupropion (Wellbutrin and Zyban) on average had a 15% lower risk of gaining a clinically According to Harvard Medical School, the reason why some antidepressants might cause weight gain could be linked to serotonin levels in the brain. 2 pounds (0. “In our study, the average weight at baseline was 84 kg Antidepressants are among the most commonly prescribed medications in the U. Get coupon. Effexor (venlafaxine) Effexor is commonly prescribed when anxiety and depression occur together, per this study. They are effective against depression and anxiety. 15 A UK study analysed data for 268 patients treated with antidepressants from a general practice with 11 994 registered Here are a couple of figures showing weight change during acute treatment (4-12 weeks after starting treatment) and maintenance (at least 4 months after starting treatment). Generally speaking, some antidepressants seem more likely to cause weight gain than others. Treatment choices are largely based on adverse effects, costs, and other factors. While we know there is a connection between depression Jul 2, 2024 · Duloxetine was associated with an average gain of 1. Online ahead Jul 5, 2024 · Weight gain has long been a common side effect of antidepressants, but some of them are more likely to add pounds than others, according to a new study. Jan 16, 2024 · Older antidepressants like the tricyclic antidepressants (TCAs), for example amitriptyline or doxepin, cause more weight gain than the SSRIs but are infrequently prescribed today for depression. Antidepressants can also affect metabolism, leading to a slower rate of burning calories. And other possible side effects of antidepressants , such as nausea and insomnia, may affect eating habits and weight. Reply. Other antidepressants contributed to users gaining more than 5% of their baseline weight at just the six-month mark. Other people might lose weight due to reduced appetite associated with the Apr 6, 2021 · The amount of weight you gain depends on the type of medicine you’re taking, how your body responds to it, and other factors, such as how much you eat and exercise. adults reporting using an antidepressant. Nov 13, 2023 · November 13, 2023. 6 7 9 10 20 None of those studies had Mar 30, 2022 · Weight loss; Increased appetite leading to weight gain; Excessive sweating; Tremor; Sexual problems, such as difficulty achieving an erection, delayed orgasm or low sex drive; Generally speaking: Amitriptyline, doxepin, imipramine and trimipramine are more likely to make you sleepy than other tricyclic antidepressants are. Keep in mind that antidepressants are more likely to reduce suicide risk in the long run by improving mood. According to Mayo Clinic, nearly all antidepressants have the potential to cause weight gain. I imagine weight gain is a common side effect of the majority of antidepressant drugs, despite the numerous classes. Fava, M. Weight gain is an adverse effect of antidepressants and antipsychotics. And like hair loss, gaining weight should not be justification for refusing treatment Jul 4, 2024 · As weight gain may impact medication adherence, clinicians should consider potential weight gain when initiating patients on antidepressant treatment. “In general, weight gain is a possible side effect of most antidepressants, such as Zoloft, Prozac or Celexa, but each person will react to antidepressants differently,” Naidoo says. Antidepressant utilisation and incidence of weight gain during 10 years May 16, 2018 · One study evaluated weight change after initiation of antidepressant treatment in 5932 patients registered with the Group Health system in Washington state, USA, and found that weight gain persisted for at least two years. In this article, we will explore the role of Pristiq in mental health, the connection between antidepressants and weight gain, what the research Sep 7, 2010 · Accordingly, the aim of this study is to examine whether exposure to antidepressant medication use is associated with type 2 diabetes risk in a large population of men and women (Aim 1) and whether there is a difference in weight gain among antidepressant users compared with equally depressed individuals who are not treated with antidepressants May 23, 2018 · Results In the year of study entry, 17 803 (13. Taking these Antidepressants and Body Weight weight, in order to improve the well-being of patients and prevent medical illness associated to obesity. Sep 16, 2019 · Most of the included studies showed a 5% weight gain in individuals using antidepressant therapy, however, Quetiapine, Haloperidol, Trifluoperazine, Risperidone, Aripiprazole, Olanzapine and Clozapine increased body weight ≥7% from baseline, which is considered a clinically significant result. Zoloft worked well for me and didn't cause weight gain. Most antidepressants have similar efficacy. Effexor (venlafaxine) is an antidepressant that works by preventing serotonin and norepinephrine from being reabsorbed into the neuron. 4. 2 pounds of weight gain. Citalopram (Celexa) and weight gain – studies found less than 1% of people reported weight changes on citalopram (Celexa). Researchers analyzed the health information of more than 300,000 people in the United Kingdom (average age 51) who'd had their weight and body mass index measured at doctor appointments between 2004 and 2014. However, I completely understand your concern. SSRIs include fluoxetine (Prozac), paroxetine (Paxil, Pexeva), sertraline (Zoloft), citalopram (Celexa) and escitalopram (Lexapro). dankekm21 June 2018. 6 7 9 10 20 However, in those previous population studies, lifestyle factors were either lacking or treated as confounding factors. While the short term risk of weight gain has been well described, 5 the longer term risk (>1 year) remains poorly investigated. Researchers at King’s College London found that all twelve of the leading Apr 29, 2022 · Depression is known to cause weight changes. Antidepressants are also Jul 8, 2024 · Duloxetine was linked to 1. Remeron, Paxil, and amitriptyline are antidepressants known to cause weight gain in people who take them. JAMA Psychiatry, 71(8):889-896. We will discuss the literature with respect to the following issues: weight gain as a pharmacological effect of antidepressants or as an effect of recovery from depression; the incidence of antidepressant-induced weight gain and possible reasons for individual variability in its Statistically, again, it varies among antidepressants, in many double blind trials patients reported weight gain as a placebo as well. Lexapro (escitalopram) Get coupon. May 25, 2022 · The five antidepressants that cause the least weight gain are Effexor (venlafaxine), Wellbutrin (bupropion), amitriptyline, nortriptyline, and Nefazodone (rarely used because of liver problems). Citation. However, while there is Jan 16, 2017 · WebMD reports that up to 25 percent of people who are prescribed medications to treat depression, including SSRIs and other common types of antidepressants, will experience weight gain to the tune of 10 pounds or more. However, each person responds to antidepressants differently. Abstract. Jul 18, 2022 · However, many antidepressants are also used for the treatment of anxiety, and may cause weight gain as discussed above. Most antidepressants make you feel better and your appetite improves as a result. K. These antidepressants generally cause fewer bothersome side effects and are less likely to cause problems at higher therapeutic doses than other types of antidepressants. We also evaluated the associations in different subgroups and whether individual Nov 10, 2023 · Some antidepressants will not cause weight gain — some can even cause weight loss. While not all antidepressants cause weight gain, some are more likely to than others. However, significant weight gain during the acute phase of treatment or weight gain that continues despite achieving full remission of depressive symptoms is likely to be a side effect of antidepressant treatment. However, most antidepressants have numerous documented adverse events, including cardiometabolic effects and weight gain, which are major public health concerns. Jun 7, 2018 · Antidepressants are associated with significant weight gain, according to a new long-term study published in the BMJ. MAOIs that bind irreversibly to receptors (eg, phenelzine, isocarboxazid Some adverse effects, such as sedation, may be more acceptable to patients, but others such as weight gain may be less acceptable. Regarding antidepressants, weight gain can be a common side effect. 2 kilograms) at six months Mar 15, 2023 · 1. Oct 17, 2023 · Weight gain can be a common side effect of both acute and long-term usage of antidepressants. 17 In this study we used primary care electronic health records to evaluate non-randomised evidence on the long term association of antidepressant prescribing with weight gain. May 3, 2022 · Which antidepressant you take may influence whether or not you gain weight. Jul 5, 2024 · How common antidepressants are linked to weight gain. • 33 min. Answer Section. Medication-induced weight change across common antidepressant treatments: a target trial emulation study. Turbulent_Fix_5123. Jun 26, 2018 · In this population-based cohort study, U. This side effect can lead to numerous comorbidities and reduces life expectancy. 6% of SSRI users had gained weight within a four-year time frame. Weight gain is a common side effect, which could affect Study investigators compared weight at six, 12, and 24 months after initiation of eight common antidepressants: sertraline, citalopram, escitalopram, fluoxetine, paroxetine, bupropion, duloxetine Jul 2, 2024 · Taking Cymbalta, Lexapro, or Paxil was linked to a 10% to 15% higher risk of weight gain. One way is by blocking histamine 1 receptors. 2 days ago · Weight gain from antidepressants can result from a combination of increased appetite, metabolic and hormonal changes affecting hunger and fat storage, explains Sarah Oreck, MD, Reproductive Oct 17, 2022 · Antidepressants can also cause weight loss or weight gain. ibwk. Some people may lose weight due to a loss of appetite. There is evidence that antidepressant drugs may induce a variable amount of weight One antidepressant contributed to a small amount of weight loss at six months, the study found. One systematic review of 27 clinical studies found that most antidepressants caused an average weight gain of five pounds — but the drug bupropion (Wellbutrin) actually triggered weight loss. In one recent large study, involving nearly 300,000 people, people who had used an antidepressant for more than a year were found to be at Sep 16, 2019 · Weight gain is an adverse effect of antidepressants and antipsychotics. There is evidence that antidepressant drugs may induce a variable amount of weight gain, but results are sparse and often contradictory. Even on antidepressants that cause this side effect, the typical weight gain is minimal–a few pounds. 2. ago. Like hair loss during chemotherapy, weight gain while on antidepressants is not, fortunately, inevitable. Which antidepressant is best for you depends on a number of issues, such as your symptoms and any other health conditions you may have. References. Votes: +0. The severity of the weight gain varies with the drug, with some causing weight Dec 7, 2010 · Clinically, weight gain is a common occurrence during both acute and long-term treatment with antidepressants, 22 and it is a major problem for two reasons: (1) depressed patients are already at increased risk of cardiovascular disease, 23 and weight gain could worsen that risk; and (2) weight gain is a cause of decreased antidepressant Jul 18, 2022 · However, many antidepressants are also used for the treatment of anxiety, and may cause weight gain as discussed above. Be aware that patients might have misinformation from the internet or through word of mouth that the adverse effects of an antidepressant are ‘dreadful and nobody should ever take it’. With more than 2 in 3 adults nationwide overweight or obese, the long-term effects of these medicines on weight is a significant public health concern. Mar 27, 2019 · Weight gain can be a side effect of certain antidepressants. While gaining weight on antidepressants is far from inevitable (it all depends on how your body responds to that particular medication), it would be remiss to ignore the possibility. 7 pounds (0. Petimar J, Young JG, Yu H, et al. Every medication carries potential May 23, 2018 · The risk of weight gain associated with antidepressant treatment has received particular attention because of the increased risk of chronic disease and mortality related to being overweight and obese. Appetite regulation and weight gain Jun 13, 2022 · The bottom line. Weight gain (WG) during antidepressant treatment can be either a sign of improvement in patients who have weight loss as a symptom of depression or a residual symptom in patients who overeat when depressed. Mirtazapine (Remeron), a tetracyclic antidepressant, is known to be associated with significant weight gain. Mar 10, 2023 · Pristiq, a commonly prescribed antidepressant, has been associated with weight gain in some individuals. 55 kilograms) at six months and 1. The only medicine I personally noticed has ever made me gain weight is combination birth control pills. The exception to this is Prozac, which doesn’t seem to affect weight for most people. Mar 1, 2017 · Furthermore, weight gain is a serious problem that can compromise adherence to psychotropic drug regimens and lead to symptomatic relapse and medical comorbidity. While there are some antidepressants that cause weight loss, others are associated with weight gain. I’ve lost weight on some and gained weight on some. Ann Intern Med. 4%) women with a mean age of 51. Celexa. adults reported having ever been diagnosed with depression. However, each person responds differently to OBJECTIVE: Psychotropic drugs often induce weight gain, leading to discomfort and discontinuation of treatment and, more importantly, increasing the risk of obesity-related illnesses such as diabetes mellitus, hypertension, and coronary heart disease. While not everyone experiences this side effect, it is important to understand how Pristiq functions and why it may lead to changes in weight. 7 pounds, and Zoloft led to 3. , with 14% of U. And many studies suggest that the weight gain is more likely if the drug is used for six months or more. Antidepressant agents provide varying risk of associated weight gain After starting on antidepressants, some people might feel better and regain their appetite, leading to weight gain. [5] Fava M. 2 kg, which is similar to those reported in the literature for shorter studies. On the other hand, increased appetite, carbohy-drate craving, and weight gain can also be symptoms of depression, in particular among depressed patients with atypical features. Many individuals have the experience of weight gain while receiving treatment with an antidepressant, and often wonder if selective serotonin reuptake inhibitors (SSRIs) are associated with weight gain. Antidepressant medications are the first-line treatment option for moderate to severe major depressive disorder. Even though weight gain is now seen as an almost inevitable side effect of many antidepressants and mood stabilizers, strategies for preventing Jun 19, 2024 · Learn how certain antidepressants in the class of selective serotonin reuptake inhibitors (SSRIs) can cause weight gain or loss, and what you can do to manage your weight while taking them. 5 days ago · Some antidepressants are more likely to cause weight gain; here is a list of some antidepressants and information on weight gain. Jan 24, 2024 · A follow-up study found that 4. Reply reply. It may help you so that you stop binge eating. Discover the effects that other antidepressants can have on Jan 21, 2015 · 12. Although some selective serotonin reuptake inhibitors (SSRIs) may cause weight loss during the early stages Apr 8, 2024 · Weight changes are considered a side effect for both Wellbutrin XL and Wellbutrin SR. It tends to cause less weight gain and may have a lower risk of causing insomnia than some SSRIs. Antidepressant Aug 10, 2018 · Information about possible weight gain and sedation is given for each of the 143 psychiatric drugs listed, but I will focus on only the antidepressants and their potential risk for weight gain. Antidepressant-induced weight gain varied between 6 classes of antidepressants. Serotonin and norepinephrine reuptake Jun 4, 2014 · The researchers looked at the electronic medical records of 22,610 adults on antidepressants and compared their reported weight gain over a year. It also has fewer drug interactions, which can be helpful if you’re taking other medications. The study, published Monday in the journal SSRIs treat depression by increasing levels of serotonin in the brain. Some people gain weight when taking a certain antidepressant, while others don’t. 5 years (SD 16. Acute. Studies of Wellbutrin XL show that 23% of people taking a dose of 150 to 300 mg per day lost 5 pounds or more. Each person's situation is difference, and their response may vary. In 2020, 18% of U. This side effect can lead Sep 21, 2023 · Weight gain is a potential side effect of any antidepressant medication, but some antidepressants are less likely to result in weight gain – and may even result in weight loss. S. Learn the other causes of weight gain when taking antidepressants and how to manage weight. DA. Weight gain and antidepressants. This makes more serotonin available to improve transmission of messages between neurons. 6 years) were prescribed antidepressants. Gulliford MC. Some antidepressants actually cause weight loss as a side effect. 1 per 100 person years and in participants prescribed antidepressants was 11. Sep 10, 2018 · Needed: A weight loss plan for those on medication. In the same studies, 11% of people gained more than 5 pounds. And research has shown that up to 25% of the people who take antidepressant medications may also experience weight gain. SSRIs block the reabsorption (reuptake) of serotonin into neurons. Weight gain is a possible side effect of nearly all antidepressants. Not all antidepressants cause weight gain, and even those that do may not affect everyone the same way. Needless to say, finding yourself in that group can be very frustrating. (Diabetes Care, 2010) A systematic review of all SSRIs found that Paroxetine was most likely to be associated with weight gain, while Bupropion and Nefazodone were the least likely to cause weight gain. However, if there is a higher risk for antidepressant-related weight Enough people gain weight on antidepressants to make this side effect a major problem, especially since for many it becomes a choice between decreasing depression and gaining weight or being Oct 5, 2019 · Anyone taking an antidepressant should be watched closely for worsening depression or unusual behavior. Lexapro and most other SSRIs are more likely to cause weight gain if you take them long term. qe ij mm ns pe cj cn gi cv eu